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One of the women on this list who truly deserves the title Acid Head, Joplin was a true child of the hippie movement, an advocate of the ’60s vibe, and a major drug user. Despite – or perhaps because of – tragically dying of a heroin overdose at the age of 27, her legacy in the chemical hall of fame was sealed in the lexicon of pop culture. She even had a sheet of acid blotter posthumously designed for her by Robert Crumb!